Remember paclitaxel?
I refer you to 'The treatment conversation I and II' way back in the day... Entangled Lives by Melvyn Sheldrake was a welcome Christmas present. I haven't got far into it but have already gone down a fascinating wormhole after reading that paclitaxel is made by fungi living in the yew trees. The fungi are endophytes (living inside plants) and it would appear there are loads of them. It seems that both the yew tree and some or all of the fungi living there are making the compound. It also seems that there are a lot of fungi living there. One study found 150 fungal species in common yew in Iran, a Chinese study found 81 species with at least three producing paclitaxel, another Chinese study found 528 'strains' of endophytic fungi in In 2015 Science Direct summarised an article from Current Biology about this - https://www.sciencedirect.com/science/article/pii/S0960982215011793 . Yews grow in a way that should leave them particularly open to wood-degrading fungi;...